Have you already tried installing it? All we need is literally someone to install the BE200 instead of the RZ616, try to boot the laptop with it, and see what happens
If you are using the BE200 right now and it works and it gets detected then it’s golden, and we know the BE200 works on AMD boards!
The only thing that comes to mind is battery damage. Keeping your laptop constantly plugged in and heating up during intensive work / gaming sessions will speed up the rate at which the battery ages. However, it’s a Framework, so repairs are reasonably cheap and doable - so even this point has shakey ground to stand on.
Aside from that - there is no loss. I, too, use my laptop as a desktop replacement with a dock nowadays. Laptops have gotten so good that while surely desktops are still better, many users - even heavy ones - are fine with the performance output that laptops give you.