Safest and fast - Wireguard. But you need to setup duckdns too.
Safest and easiest - Tailscale. It’s a userland implementation of Wireguard with added stuff to make it stupidly easy to run. But because it’s not a kernel module, it’s slightly slower.
I certainly pause and save the game, but then I’m more than happy to leave the Deck in sleep mode to get back to it quickly.
If something goes wrong, just reboot, butt normally it doesn’t