If somebody was having issues with a weakened immune system, and also dealing with a chronically higher baseline level of inflammation, are there any known ways to strengthen the immune system while reducing or at least not increasing baseline inflammation? Is that even possible or is some level of inflammation unavoidable?

Would it depend on the specific inflammatory factors that are already causing the higher baseline response?

I know there’s some research about running reducing inflammation, but it also triggers some inflammation? Is the acute inflammation triggered by running tied to longer term reductions in inflammation?