On Earth, the cardinal directions are straightforward. The arrow on a compass points to the nearest magnetic pole. You can then use it to travel anywhere on Earth.
In space, the idea of anything being “central” enough to be used as a “North” (since the universe has no center) or being fixated enough to not somehow pose issues is more convoluted.
If you were a pioneer of space exploration, what would your “North” be?
Because as big as space is, time is bigger. Humans have existed for only the most recent nanosecond, and we’re only just figuring out how to leave this rock. We’re either going to figure out intergalactic space travel, or we might just obliterate ourselves and kill all life on the planet.
Crossing paths with another intergalactic species would be like if two different people each threw a grain of sand into the air in any desert or beach on earth at some point in the last 10,000 years, and the two grains of sand collide.
If we do find intelligent life out there, it will probably be because we have developed some intergalactic broadcast signal, and whatever comes for us might share their star maps or they might just be looking for a snack. Either way, it would take them thousands of years to hear our signal and get to us.