cross-posted from: https://lemmy.world/post/13505585

I’m going to ask my psychiatrist before making decisions about dosing, but I am looking for personal experiences.

Reason for asking: In the Microdosing Handbook, the author says that atypical antipsychotics should theoretically render mushrooms ineffective because they block the 5-HT2A serotonin receptors that psilocin acts upon.

I’m on Vraylar. However, when I took 0.5 grams of shrooms, I definitely felt some mild sensory and cognitive effects.