Just a reminder : a time without a timezone info attached is about as useless as a text file without encoding info attached. (of course this doesn’t apply to your very special snow flake script, and a few other cases)

Try this one:

results["now()"] = timeit.timeit(
    setup="import datetime; now=datetime.datetime.now", stmt="now()", number=number
)

If you’re using either of these functions to measure latency, you’re doing it wrong. You most likely want to be using time.monotonic() or time.perf_counter(), since neither will be affected by NTP updates.